Vuillemin is a surname. Notable people with the surname include:
- Alexandre Vuillemin (1812–1880), French cartographer
- David Vuillemin, French motorcycle racer
- Jean Vuillemin, French computer scientist
- Jean-Claude Vuillemin, French-born liberal-arts research professor at Penn State U.
- Jean Paul Vuillemin (1861–1932), French mycologist
- Joseph Vuillemin (1883–1963), French aviator and air force general
- Jules Vuillemin (1920–2001), French philosopher
- Louis Vuillemin (1870–1929), French composer
- Philippe Vuillemin, French cartoonist
