Resch is a surname of German origin. Notable people with the surname include:
- Alessandro Resch (1892–1966), Italian flying ace
- Alexander Resch, German luger
- Anton Resch (1921–1975), German fighter ace
- Aurélie Resch, Canadian author and filmmaker
- Chico Resch, Canadian ice hockey goaltender
- Edmund Resch (1847–1923), Australian brewer
- Erwin Resch, Austrian alpine skier
- Francis Xavier Resch (1878–1976), Austrian-born American bishop
- Franz Resch, Austrian footballer
- Friedrich Resch, Austrian equestrian
- Helmuth Resch, Austrian fencer
- Jakob Resch, West German bobsledder
- Jami Resch, American police chief
- Jutta Resch-Treuwerth (1941-2015), German journalist
- Lisa Resch (1908–1949), German alpine skier
- Nicole Resch, German jurist
- Nikolaus Resch, Austrian sailor
- Poldl Resch (1900–1971), Austrian footballer
- Riitta Resch, Finnish diplomat
- Ron Resch (1939–2009), American computer scientist and artist
- Thomas Resch (1460–1520), Austrian Renaissance humanist
- Tina Resch, U.S. citizen claiming to have psychokinetic abilities
- Tony Resch, U.S. lacrosse player
