Michael or Mike Fleming may refer to:
- Sir Michael le Fleming, 4th Baronet (1748–1806), member of parliament for Westmorland
- Michael Anthony Fleming (1792–1850), bishop of Newfoundland
- Michael P. Fleming, Texas-based lawyer
- Michael Fleming (historian), professor of history at the Polish University Abroad in London
- Mike Fleming, American conservative radio talk show host
- Mike Fleming (footballer), English footballer
- Mick Fleming, Irish Gaelic footballer
- Michael Fleming (MP) (1668–1718), member of parliament for Westmorland, 1707–1708
- Michael Fleming (musician), American jazz bassist; see I Talk with the Spirits
