KLIC may refer to:
- KLIC (AM), a defunct radio station licensed to serve Richwood, Louisiana, United States
- Klíč (mountain), a peak of the Lusatian Mountains
- The Key , a 1971 Czech film
- Kulicke & Soffa Industries
- Kullback–Leibler divergence
- Klic, former stage name of the British House music artist Medlar