KIRO may refer to:
- KIRO (AM), a radio station licensed to Seattle, Washington, United States
- KIRO-TV, a television station licensed to Seattle, Washington, United States
- KIRO-FM, a radio station licensed to Tacoma, Washington, United States
- KKWF, a radio station licensed to Seattle, Washington, United States, which used the call sign KIRO-FM from September 1992 to May 1999
- Kiro, a colonial post in what is now the Central Equatoria province of South Sudan
- Kiro, a Macedonian name and it come from a Greek word "Kyrios"