Christakis is a name of Greek origin and may refer to:
- Surname
- Alexander Christakis, Greek-American social scientist, systems scientist and cyberneticist
- Erika Christakis, American expert in early childhood education
- Georgios Christakis-Zografos (1863–1920), Greek politician
- Nicholas A. Christakis, American physician and social scientist
- Given name
- Christakis Charalambides, primate of the Estonian Apostolic Orthodox Church
- Christakis Zografos (1820–1898), Greek banker
