Antonioli is an Italian surname. Notable people with the surname include:
- Claudio Antonioli, retired Italian racing driver
- Dan Antonioli, builder and owner of two evolving intentional communities
- Fausto Antonioli (1814–1882), Italian painter
- Francesco Antonioli, Italian footballer and goalkeeper
- Jean-François Antonioli, Swiss pianist, conductor and piano pedagogue
- Laurie Antonioli, American jazz singer and record producer
- Michele Antonioli, Italian short track speed skater
- Robert Antonioli, Italian ski mountaineer
- Roberto Antonioli, Italian rugby union and professional rugby league footballer
