AICO may refer to:
- A.I.C.O. -Incarnation-, a Japanese science fiction original net animation (ONA) anime series
- American Innovation and Choice Online Act, proposed antitrust legislation in the United States Congress
- ASEAN Industrial Cooperation Scheme, an industrial initiative established by the Association of Southeast Asian Nations; see Automotive industry in Thailand
- Indigenous Authorities of Colombia, a Colombian political party of indigenous people
- Eido II, bishop of Meissen from 1040 to 1045 or 1046
