ACMF may refer to:
- Allied Central Mediterranean Force, a force consisting of the US Fifth Army and the British Eighth Army during World War II.
- Adriamycin, Cyclophosphamide, Methotrexate, and 5-Fluorouracil, a chemotherapy regimen used in the treatment of breast cancer
- Arachnoid Cysts of the Middle Fossa, the most common location where intracranial arachnoid cysts are found
- Adivasi Cobra Militant Force, a militant adivasi organization in Assam
- Antimatter/Antiproton Catalyzed Micro Fission/Fusion, a future technology being developed for long-distance space travel
- Two similarly named country music organizations use this acronym:
- Austrian Country Music Federation
- Australian Country Music Foundation
